Metabolic Regulation of Hematopoietic Stem Cells

Metabolic Regulation of Hematopoietic Stem Cells

Cellular metabolism is a key regulator of hematopoietic stem cell (HSC) maintenance. HSCs rely on anaerobic glycolysis for energy production to minimize the production of reactive oxygen species and shift toward mitochondrial oxidative phosphorylation upon differentiation. However, increasing eviden...

Full description

Bibliographic Details
Main Authors:	Claudia Morganti, Nina Cabezas-Wallscheid, Keisuke Ito
Format:	Article
Language:	English
Published:	Wiley 2022-07-01
Series:	HemaSphere
Online Access:	http://journals.lww.com/10.1097/HS9.0000000000000740

Similar Items

Targeted LC-MS/MS-based metabolomics and lipidomics on limited hematopoietic stem cell numbers
by: Katharina Schönberger, et al.
Published: (2022-06-01)

VarID2 quantifies gene expression noise dynamics and unveils functional heterogeneity of ageing hematopoietic stem cells
by: Reyna Edith Rosales-Alvarez, et al.
Published: (2023-06-01)

Lysosomes and Their Role in Regulating the Metabolism of Hematopoietic Stem Cells
by: Tasleem Arif
Published: (2022-09-01)

Crosstalk between DNA Damage Repair and Metabolic Regulation in Hematopoietic Stem Cells
by: Jian Xu, et al.
Published: (2024-04-01)

Regulating traffic in the hematopoietic stem cell niche
by: Marc H.G.P. Raaijmakers
Published: (2010-09-01)

Regulation of hematopoietic stem cell activity by inflammation
by: Laura eSchuettpelz, et al.
Published: (2013-07-01)

Regulation of hematopoietic and leukemia stem cells by regulatory T cells
by: Carsten Riether, et al.
Published: (2022-11-01)

Endocytosis as a critical regulator of hematopoietic stem cell fate —implications for hematopoietic stem cell and gene therapy
by: Prathibha Babu Chandraprabha, et al.
Published: (2024-09-01)

The regulation of hematopoietic stem cell fate in the context of radiation
by: Yukai Lu, et al.
Published: (2020-03-01)

ERK1 regulates the hematopoietic stem cell niches.
by: Nathalie Saulnier, et al.
Published: (2012-01-01)

Mitochondria underlie different metabolism of hematopoietic stem and progenitor cells
by: Lorena Arranz, et al.
Published: (2013-07-01)

Lineage-biased hematopoietic stem cells are regulated by distinct niches
by: Pinho, S, et al.
Published: (2018)

Cited2 is an essential regulator of adult hematopoietic stem cells.
by: Kranc, K, et al.
Published: (2009)

CD11a regulates hematopoietic stem and progenitor cells
by: Lifei Hou, et al.
Published: (2023-09-01)

Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells
by: Gazit, Roi, et al.
Published: (2014)

Approaches towards Elucidating the Metabolic Program of Hematopoietic Stem/Progenitor Cells
by: Hiroshi Kobayashi, et al.
Published: (2022-10-01)

BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state
by: Muran Xiao, et al.
Published: (2023-12-01)

AB0-incompatible allogeneic hematopoietic stem cell transplantation
by: Nina Worel, et al.
Published: (2008-11-01)

Interleukin-1 regulates hematopoietic progenitor and stem cells in the midgestation mouse fetal liver
by: Claudia Orelio, et al.
Published: (2009-04-01)

Hematopoietic stem cell mobilization
by: Roberto M. Lemoli, et al.
Published: (2008-03-01)

Hematopoietic stem cell mobilization
by: Hsin-Hou Chang, et al.
Published: (2022-01-01)

Hematopoietic stem cell protocols /
by: Bunting, Kevin D.
Published: (2008)

WBP1L regulates hematopoietic stem cell function and T cell development
by: Imtissal Krayem, et al.
Published: (2024-11-01)

Hematopoietic stem cells: Understanding the mechanisms to unleash the therapeutic potential of hematopoietic stem cell transplantation
by: Amjad Ahmed Aljagthmi, et al.
Published: (2025-02-01)

Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size
by: Runfeng Miao, et al.
Published: (2022-08-01)

Fev regulates hematopoietic stem cell development via ERK signaling.
by: Wang, L, et al.
Published: (2013)

The role of CD44 in fetal and adult hematopoietic stem cell regulation
by: Huimin Cao, et al.
Published: (2016-01-01)

Wip1 regulates hematopoietic stem cell development in the mouse embryo
by: Wenyan He, et al.
Published: (2020-02-01)

Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance
by: Cuiping Zhang, et al.
Published: (2020-03-01)

YTHDF3 as a new player in hematopoietic stem cell regulation
by: Xinjian Mao, et al.
Published: (2022-02-01)

CK2β Regulates Hematopoietic Stem Cell Biology and Erythropoiesis
by: Laura Quotti Tubi, et al.
Published: (2023-12-01)

External signals regulate continuous transcriptional states in hematopoietic stem cells
by: Eva M Fast, et al.
Published: (2021-12-01)

DLK1 IS A NEGATIVE REGULATOR OF EMERGING HEMATOPOIETIC STEM CELLS
by: Ottersbach, K, et al.
Published: (2011)

The Ins and Outs of Autophagy and Metabolism in Hematopoietic and Leukemic Stem Cells: Food for Thought
by: Angela Ianniciello, et al.
Published: (2018-09-01)

Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche
by: Heather A. Himburg, et al.
Published: (2012-10-01)

Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche
by: Heather A. Himburg, et al.
Published: (2012-12-01)

Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells.
by: Mirshekar-Syahkal, B, et al.
Published: (2013)

Computational promoter modeling identifies the modes of transcriptional regulation in hematopoietic stem cells.
by: Sung-Joon Park, et al.
Published: (2014-01-01)

Osteomacs interact with megakaryocytes and osteoblasts to regulate murine hematopoietic stem cell function
by: Safa F. Mohamad, et al.
Published: (2017-12-01)

Ginsenoside Rg1 as a Potential Regulator of Hematopoietic Stem/Progenitor Cells
by: Fang He, et al.
Published: (2021-01-01)