Potential targets and mechanisms of Guarana in the treatment of Alzheimer’s disease based on network pharmacology

Potential targets and mechanisms of Guarana in the treatment of Alzheimer’s disease based on network pharmacology

Objective: To dig the main active components and predict potential mechanisms of Guarana in the treatment of Alzheimer’s disease (AD) by network pharmacology method and molecular docking. Methods: By digging into papers relating to this topic, chemical components in Guarana were obtained and used fo...

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Manylion Llyfryddiaeth
Prif Awduron:	J.I.A.O. Zhilin, G.A.O. Xuemei
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	KeAi Communications Co., Ltd. 2023-03-01
Cyfres:	Digital Chinese Medicine
Pynciau:	[Key words] Guarana (Paullinia cupana) Alzheimer's disease network pharmacology β-Amyloid molecular docking
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2589377723000174

Eitemau Tebyg

PROPIEDADES QUÍMICAS Y FARMACOLÓGICAS DEL FRUTO GUARANÁ (Paullinia cupana) CHEMICAL AND PHARMACOLOGICAL PROPERTIES OF THE FRUIT GUARANÁ (Paullinia cupana)
gan: Eugenia M. KUSKOSKI, et al.
Cyhoeddwyd: (2005-03-01)

Effects of guarana (Paullinia cupana) powder on obesity-associated diseases in animal models: A systematic review
gan: Clécia Dias Teixeira, et al.
Cyhoeddwyd: (2024-01-01)

Effect of crude extract and its semi purified constituents from guaraná seeds [Paullinia cupana var. sorbilis (Mart.) lucke] on cognitive performance in Morris water maze in rats
gan: Fernanda Jacques Otobone, et al.
Cyhoeddwyd: (2005-09-01)

Preventive treatment with guarana powder (Paullinia cupana) mitigates acute paracetamol-induced hepatotoxicity by modulating oxidative stress
gan: Clécia Dias Teixeira, et al.
Cyhoeddwyd: (2025-06-01)

Development and validation of an analytical method by HPLC-DAD for determination of caffeine in products based on guarana extracts (Paullinia cupana)
gan: Anna Kelly Moura-Silva, et al.
Cyhoeddwyd: (2023-05-01)

Dissolution test of herbal medicines containing Paullinia cupana: validation of methods for quantification and assessment of dissolution
gan: Sandra Alves de Sousa, et al.
Cyhoeddwyd: (2011-06-01)

Guarana (Paullinia cupana) as a potential tool for mesenchymal stromal cells priming in regenerative medicine
gan: D.H. Sirena, et al.
Cyhoeddwyd: (2024-07-01)

Anti-Aging and Antioxidant Potential of Paullinia cupana var. sorbilis: Findings in Caenorhabditis elegans Indicate a New Utilization for Roasted Seeds of Guarana
gan: Herbenya Peixoto, et al.
Cyhoeddwyd: (2017-08-01)

Guarana (Paullinia cupana) presents a safe and effective anti-fatigue profile in patients with chronic kidney disease: A randomized, double-blind, three-arm, controlled clinical trial
gan: Ieda Maria Pedroso Dorneles, et al.
Cyhoeddwyd: (2018-12-01)

Colletotrichum siamense, a Mycovirus-Carrying Endophyte, as a Biological Control Strategy for Anthracnose in Guarana Plants
gan: Luana Lopes Casas, et al.
Cyhoeddwyd: (2021-10-01)

Period of Weed Interference in Guarana Crop
gan: D.O.P. SOARES, et al.

Guarana propagation strategies: a review
gan: A. P. Nascimento, et al.
Cyhoeddwyd: (2023-12-01)

Scientific Opinion on the substantiation of a health claim related to a combination of <em>Paullinia cupana</em> Kunth (guarana) and <em>Camellia sinensis</em> (L.) Kuntze (green tea) extracts and reduction of body weight pursuant to Article 13(5) of Regulation (EC) No 1924/2006
gan: EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
Cyhoeddwyd: (2012-12-01)

Adaptabilidade e estabilidade de clones de guaraná Adaptability and phenotypic stability in guarana clones
gan: Firmino José do Nascimento Filho, et al.
Cyhoeddwyd: (2009-09-01)

Acute efects of the Paulinia cupana, "Guaraná" on the cognition of normal volunteers
gan: José Carlos Fernandes Galduróz, et al.

The effects of long-term administration of guarana on the cognition of normal, elderly volunteers
gan: Jose Carlos Fernandes Galduróz, et al.

Using Glyphosate on Guarana Seedlings in the Amazon
gan: Bruna Nogueira Leite Konrad, et al.
Cyhoeddwyd: (2023-07-01)

Associação entre características da parte aérea e do sistema radicular em mudas de guaranazeiro por correlações canônicas Canonical correlations among characteristics of shoots and roots system in guarana seedlings
gan: Firmino José do Nascimento Filho, et al.
Cyhoeddwyd: (2012-06-01)

Adding guarana powder to medfly diets: an alternative for improving the Sterile Insect Technique
gan: Jamile Câmara de Aquino, et al.
Cyhoeddwyd: (2016-06-01)

Indole-3-butyric Acid Improves Root System Quality in Guarana Cuttings
gan: Karla Gabrielle Dutra Pinto, et al.
Cyhoeddwyd: (2020-09-01)

Health and technological aspects of methylxanthines and polyphenols from guarana: A review
gan: Ádina L. Santana, et al.
Cyhoeddwyd: (2018-08-01)

Repetibilidade da produção de sementes em clones de guaraná Seed yield repeatability of guarana clones
gan: Firmino José do Nascimento Filho, et al.
Cyhoeddwyd: (2009-06-01)

Rooting Conditions for Production of Guarana Clonal Seedlings
gan: Karla Gabrielle Dutra Pinto, et al.
Cyhoeddwyd: (2024-11-01)

Enraizamento de estacas herbáceas de guaranazeiro em diferentes substratos Survival rate of guarana herbaceous cuttings in different substrates
gan: Murilo Rodrigues de Arruda, et al.
Cyhoeddwyd: (2007-02-01)

On the occurrence of cyanolipids In Paullinia carpopodea cambess And P. cupana Kunth seed oils
gan: Regina C. A. LAGO, et al.
Cyhoeddwyd: (2000-03-01)

Microencapsulation of Carotenoid-Rich Extract from Guaraná Peels and Study of Microparticle Functionality through Incorporation into an Oatmeal Paste
gan: Lorena Silva Pinho, et al.
Cyhoeddwyd: (2023-03-01)

Optimized green synthesis of silver nanoparticles from guarana seed skin extract with antibacterial potential
gan: Botinelly Nogueira Rodrigo, et al.
Cyhoeddwyd: (2025-01-01)

Profiling and Evaluation of the Effect of Guarana-Loaded Liposomes on Different Skin Cell Lines: An In Vitro Study
gan: Isabel Roggia, et al.
Cyhoeddwyd: (2023-05-01)

Guaraná - Paullinia cupana, (H.B.K): Estudo da oxidação das formas em pó e em bastões defumados
gan: Wilson Gomes da Silva, et al.
Cyhoeddwyd: (2015-02-01)

Enraizamento de estacas de cultivares de guaranazeiro com adubação de plantas matrizes
gan: Sônia Maria Figueiredo Albertino, et al.
Cyhoeddwyd: (2012-10-01)

Nocturnal Bee Pollinators Are Attracted to Guarana Flowers by Their Scents
gan: Cristiane Krug, et al.
Cyhoeddwyd: (2018-07-01)

Physiological and anatomical characteristics of leaves of two clones of guarana Características fisiológicas e anatômicas de folhas de dois clones de guaraná
gan: José Francisco de Carvalho Gonçalves, et al.
Cyhoeddwyd: (2006-03-01)

Spectrophotometric determination of tannins and caffeine in preparations from Paullinia cupana var. sorbilis
gan: Maria Inez de Godoy Pelozo, et al.
Cyhoeddwyd: (2008-06-01)

Paullinia cupana para o controle de fogachos em pacientes com câncer de mama: um estudo piloto
gan: Saulo Silva Oliveira, et al.

Obtenção de extratos de guaraná ricos em cafeína por processo enzimático e adsorção de taninos Production of caffeine-rich guarana extracts using an enzymatic process and tannin adsorption
gan: Bernardo Dias Ribeiro, et al.
Cyhoeddwyd: (2012-09-01)

Antioxidant Capacity and In Vitro Prevention of Dental Plaque Formation by Extracts and Condensed Tannins of Paullinia cupana
gan: JoÃƒÂ£o Carlos Palazzo de Mello, et al.
Cyhoeddwyd: (2007-08-01)

Efeito ergogênico da suplementação aguda de pó de guaraná em lutadores de Jiu-Jitsu
gan: Jacqueline Queiroz Silveira, et al.
Cyhoeddwyd: (2018-03-01)

Folkcomunicação e turismo cultural na Festa do Guaraná de Maués (AM)
gan: Ivânia Vieira, et al.
Cyhoeddwyd: (2019-06-01)

Seleção de clones de guaranazeiro para adaptabilidade e estabilidade no estado do Amazonas
gan: Carlos Enrique Daniel Lopez Pinto, et al.
Cyhoeddwyd: (2018-10-01)

An integrated network pharmacology and molecular modelling study of phytoconstituents targeting Alzheimer's disease
gan: Saumya Khanna, et al.
Cyhoeddwyd: (2024-12-01)