MicroRNA-887-3p Inhibited MDM4 Expression and Proliferation but Promoted Apoptosis of Intervertebral Disc Annulus Fibrosus Cells in Rats

MicroRNA-887-3p Inhibited MDM4 Expression and Proliferation but Promoted Apoptosis of Intervertebral Disc Annulus Fibrosus Cells in Rats

ObjectiveTo investigate the effects of microRNA (miRNA, miR)-887-3p on the proliferation and apoptosis of rat intervertebral disc annulus fibrosus cells and its underlying molecular mechanism.MethodsAnnulus fibrosus tissues were obtained from 8-week-old SPF-grade SD male rats, centrifuged to prepare...

Full description

Bibliographic Details
Main Authors: ZHU Xiaoyu, YUAN Hantao, LI Sibo
Format: Article
Language:zho
Published: Editorial Office of Laboratory Animal and Comparative Medicine 2024-06-01
Series:Shiyan dongwu yu bijiao yixue
Subjects:
mir-887-3p
intervertebral disc annulus fibrosus cells
degenerative model
cell proliferation
apoptosis
rats
Online Access:https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2024.003

Internet

https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2024.003

Similar Items