Hydroxysafflor Yellow A Attenuates the Apoptosis of Peripheral Blood CD4+ T Lymphocytes in a Murine Model of Sepsis

Hydroxysafflor Yellow A Attenuates the Apoptosis of Peripheral Blood CD4+ T Lymphocytes in a Murine Model of Sepsis

Sepsis is generally considered as a severe condition of inflammation that leads to lymphocyte apoptosis and multiple organ dysfunction. Hydroxysafflor yellow A (HSYA) exerts anti-inflammatory and anti-apoptotic effects in infectious diseases. However, the therapeutic effect of HSYA on polymicrobial...

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Bibliographic Details
Main Authors: Jinping Wang, Ping Wang, Shuiqing Gui, Yun Li, Runhua Chen, Renqing Zeng, Peiyan Zhao, Hanwei Wu, Zheyu Huang, Jianlong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Pharmacology
Subjects:
hydroxysafflor yellow A
sepsis
CD4+ T lymphocytes
apoptosis
caspase
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00613/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00613/full

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