Relatively low level of antigen-specific monocytes detected in blood from untreated tuberculosis patients using CD4+ T-cell receptor tetramers.
The in vivo kinetics of antigen-presenting cells (APCs) in patients with advanced and convalescent tuberculosis (TB) is not well characterized. In order to target Mycobacterium tuberculosis (MTB) peptides- and HLA-DR-holding monocytes and macrophages, 2 MTB peptide-specific CD4(+) T-cell receptor (T...
Autors principals: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Idioma: | English |
Publicat: |
Public Library of Science (PLoS)
2012-01-01
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Col·lecció: | PLoS Pathogens |
Accés en línia: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003036&type=printable |