rRNA transcription is integral to phase separation and maintenance of nucleolar structure.

rRNA transcription is integral to phase separation and maintenance of nucleolar structure.

Transcription of ribosomal RNA (rRNA) by RNA Polymerase (Pol) I in the nucleolus is necessary for ribosome biogenesis, which is intimately tied to cell growth and proliferation. Perturbation of ribosome biogenesis results in tissue specific disorders termed ribosomopathies in association with altera...

Full description

Bibliographic Details
Main Authors: Soma Dash, Maureen C Lamb, Jeffrey J Lange, Mary C McKinney, Dai Tsuchiya, Fengli Guo, Xia Zhao, Timothy J Corbin, MaryEllen Kirkman, Kym Delventhal, Emma L Moore, Sean McKinney, Rita Shiang, Paul A Trainor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010854&type=printable

Internet

https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010854&type=printable

Similar Items