The aryl hydrocarbon receptor cell intrinsically promotes resident memory CD8+ T cell differentiation and function

Summary: The Aryl hydrocarbon receptor (Ahr) regulates the differentiation and function of CD4+ T cells; however, its cell-intrinsic role in CD8+ T cells remains elusive. Herein we show that Ahr acts as a promoter of resident memory CD8+ T cell (TRM) differentiation and function. Genetic ablation of...

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Bibliographic Details
Main Authors: Joseph W. Dean, Eric Y. Helm, Zheng Fu, Lifeng Xiong, Na Sun, Kristen N. Oliff, Marcus Muehlbauer, Dorina Avram, Liang Zhou
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722018678