Structural Prediction and Characterization of <i>Canavalia grandiflora</i> (ConGF) Lectin Complexed with MMP1: Unveiling the Antiglioma Potential of Legume Lectins

Structural Prediction and Characterization of <i>Canavalia grandiflora</i> (ConGF) Lectin Complexed with MMP1: Unveiling the Antiglioma Potential of Legume Lectins

A glioblastoma (GBM) is a highly malignant primary brain tumor with a poor prognosis because of its invasiveness and high resistance to current therapies. In GBMs, abnormal glycosylation patterns are associated with malignancy, which allows for the use of lectins as tools for recognition and therapy...

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Bibliographic Details
Main Authors: Rodrigo Bainy Leal, Josiane Mann, Vanir Reis Pinto-Junior, Messias Vital Oliveira, Vinicius Jose Silva Osterne, Ingrid Alessandra Victoria Wolin, Ana Paula Machado Nascimento, Priscilla Gomes Welter, Valeria Maria Sousa Ferreira, Alice Araujo Silva, Rodrigo Lopes Seeger, Kyria Santiago Nascimento, Benildo Sousa Cavada
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
glioblastoma
lectin
<i>Canavalia grandiflora</i>
matrix metalloproteinase 1
Online Access:https://www.mdpi.com/1420-3049/27/20/7089

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https://www.mdpi.com/1420-3049/27/20/7089

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