Liquid Crystalline Nanoparticles Conjugated with Dexamethasone Prevent Cisplatin Ototoxicity In Vitro

Liquid Crystalline Nanoparticles Conjugated with Dexamethasone Prevent Cisplatin Ototoxicity In Vitro

The conjugation of drugs with nanoparticles represents an innovative approach for controlled and targeted administration of therapeutic agents. Nanoparticle-based systems have been tested for the inner ear therapy, increasing the drug diffusion and being detected in all parts of the cochlea when loc...

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Bibliographic Details
Main Authors: Filippo Valente, Edi Simoni, Erica Gentilin, Alessandro Martini, Elisabetta Zanoletti, Gino Marioni, Piero Nicolai, Laura Astolfi
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
glycerol monooleate liquid crystalline nanoparticles
cubosome
hexosome
drug delivery system
OC-k3 cells
inner ear
Online Access:https://www.mdpi.com/1422-0067/23/23/14881

Internet

https://www.mdpi.com/1422-0067/23/23/14881

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