A new model for raf kinase inhibitory protein induced chemotherapeutic resistance.

Therapeutic resistance remains the most challenging aspect of treating cancer. Raf kinase inhibitory protein (RKIP) emerged as a molecule capable of sensitizing cancerous cells to radio- and chemotherapy. Moreover, this small evolutionary conserved molecule, endows significant resistance to cancer t...

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Bibliographic Details
Main Authors: Fahd Al-Mulla, Milad S Bitar, Jingwei Feng, Sungdae Park, Kam C Yeung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3261143?pdf=render