Polyvalent guide RNAs for CRISPR antivirals

Polyvalent guide RNAs for CRISPR antivirals

Summary: CRISPR effector Cas13 recognizes and degrades RNA molecules that are complementary to its guide RNA (gRNA) and possesses potential as an antiviral biotechnology because it can degrade viral mRNA and RNA genomes. Because multiplexed targeting is a critical strategy to improve viral suppressi...

Full description

Bibliographic Details
Main Authors: Rammyani Bagchi, Rachel Tinker-Kulberg, Mohammad Salehin, Tinku Supakar, Sydney Chamberlain, Ayalew Ligaba-Osena, Eric A. Josephs
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Biocomputational method
Computational bioinformatics
Biological sciences tools
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222016054

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222016054

Similar Items