Edoxaban pharmacokinetics during in vitro continuous renal replacement therapy

Edoxaban pharmacokinetics during in vitro continuous renal replacement therapy

Abstract Background To evaluate the clearance of edoxaban during modeled in vitro continuous renal replacement therapy (CRRT), assess protein binding and circuit adsorption, and provide initial dosing recommendations. Methods Edoxaban was added to the CRRT circuit and serial pre-filter bovine blood...

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Bibliographic Details
Main Authors: Eric Wenzler, Kaitlyn Dalton, Lauren Andrews, Scott T. Benken
Format: Article
Language:English
Published: BMC 2024-10-01
Series:BMC Nephrology
Subjects:
Edoxaban
Pharmacokinetics
Dialysis
Renal replacement therapy
Sieving coefficient
Saturation coefficient
Online Access:https://doi.org/10.1186/s12882-024-03777-7

Internet

https://doi.org/10.1186/s12882-024-03777-7

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