Single-cell characterization of malignant phenotypes and microenvironment alteration in retinoblastoma
Abstract Retinoblastoma (RB) is the most common primary intraocular malignancy of childhood. It is known that the tumor microenvironment (TME) regulates tumorigenesis and metastasis. However, how the malignant progression in RB is determined by the heterogeneity of tumor cells and TME remains unchar...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-05-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-04904-8 |