Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer

Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer

Abstract Background Pancreatic cancer (PAC), a malignancy that is fatal and commonly diagnosed at a late stage. Despite considerable advancements in cancer treatment, the survival rate of PAC remains largely consistent for the past 60 years. The traditional Chinese medicine formula Pulsatilla Decoct...

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Bibliographic Details
Main Authors: Rong Wu, Zhichao Xi, Mengfan Liu, Hangui Ren, Rongchen Dai, Xue Jiang, Wan Najbah Nik Nabil, Yalin Wang, Jiling Feng, Qiong Chai, Qihan Dong, Hongxi Xu
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Chinese Medicine
Subjects:
Pulsatilla Decoction
Pulsatilla
β-peltatin
Pancreatic cancer
G2/M arrest
Apoptosis
Online Access:https://doi.org/10.1186/s13020-023-00774-0

Internet

https://doi.org/10.1186/s13020-023-00774-0

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