Univariable and multivariable Mendelian randomization study identified the key role of gut microbiota in immunotherapeutic toxicity

Abstract Background In cancer patients receiving immune checkpoint inhibitors (ICIs), there is emerging evidence suggesting a correlation between gut microbiota and immune-related adverse events (irAEs). However, the exact roles of gut microbiota and the causal associations are yet to be clarified....

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Bibliographic Details
Main Authors: Baike Liu, Zheran Liu, Tianxiang Jiang, Xiangshuai Gu, Xiaonan Yin, Zhaolun Cai, Xiaoqiao Zou, Lei Dai, Bo Zhang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-024-01741-7