A PLSPM-based test statistic for detecting gene-gene co-association in genome-wide association study with case-control design.

For genome-wide association data analysis, two genes in any pathway, two SNPs in the two linked gene regions respectively or in the two linked exons respectively within one gene are often correlated with each other. We therefore proposed the concept of gene-gene co-association, which refers to the e...

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Bibliografiske detaljer
Main Authors: Xiaoshuai Zhang, Xiaowei Yang, Zhongshang Yuan, Yanxun Liu, Fangyu Li, Bin Peng, Dianwen Zhu, Jinghua Zhao, Fuzhong Xue
Format: Article
Sprog:English
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3631168?pdf=render