Bone marrow-derived dedifferentiated fat cells exhibit similar phenotype as bone marrow mesenchymal stem cells with high osteogenic differentiation and bone regeneration ability

Bone marrow-derived dedifferentiated fat cells exhibit similar phenotype as bone marrow mesenchymal stem cells with high osteogenic differentiation and bone regeneration ability

Abstract Background Mesenchymal stem cells (MSCs) are known to have different differentiation potential depending on the tissue of origin. Dedifferentiated fat cells (DFATs) are MSC-like multipotent cells that can be prepared from mature adipocytes by ceiling culture method. It is still unknown whet...

Full description

Bibliographic Details
Main Authors: Hirokatsu Sawada, Tomohiko Kazama, Yuki Nagaoka, Yoshinori Arai, Koichiro Kano, Hiroshi Uei, Yasuaki Tokuhashi, Kazuyoshi Nakanishi, Taro Matsumoto
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Dedifferentiated fat cells
Mesenchymal stem cells
Adipocytes
Cell therapy
Nonunion bone fracture
Online Access:https://doi.org/10.1186/s13018-023-03678-9

Internet

https://doi.org/10.1186/s13018-023-03678-9

Similar Items