Plasmid-based target protectors allow specific blockade of miRNA silencing activity in mammalian developmental systems

Over the past decade, microRNAs (miRNAs) have emerged as essential posttranscriptional regulators of gene expression. Though a great deal has been discovered about miRNA genomics, biogenesis, mechanisms and functions, the challenge of attributing phenotypes of altered miRNA expression to specific t...

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Bibliographic Details
Main Authors: Jennifer L Knauss, Shan eBian, Tao eSun
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00163/full