The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia–reperfusion injury by inhibiting the STING pathway

The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia–reperfusion injury by inhibiting the STING pathway

Abstract Background Astragaloside IV (As-IV) and Tanshinone IIA (Ta-IIA) are the main ingredients of traditional Chinese medicinal Astragalus membranaceus (Fisch.) Bunge and Salvia miltiorrhiza Bunge, respectively, both of which have been employed in the treatment of cardiovascular diseases. Neverth...

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Bibliographic Details
Main Authors: Pan Zhai, Qianyun Chen, Xunxun Wang, Xiaohu Ouyang, Mengling Yang, Yalan Dong, Junyi Li, Yiming Li, Shanshan Luo, Yue Liu, Xiang Cheng, Rui Zhu, Desheng Hu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Chinese Medicine
Subjects:
Tanshinone IIA
Astragaloside IV
Myocardial ischemia reperfusion injury
STING pathway
Apoptosis
Oxidative stress
Online Access:https://doi.org/10.1186/s13020-024-00908-y

Internet

https://doi.org/10.1186/s13020-024-00908-y

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