Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein?

The distinctive pathological hallmarks of Parkinson's disease are the progressive death of dopaminergic neurons and the intracellular accumulation of Lewy bodies enriched in α-synuclein protein. Several lines of evidence from the study of sporadic, familial and pharmacologically induced forms o...

Full description

Bibliographic Details
Main Authors: Victorio M. Pozo Devoto, Tomas L. Falzone
Format: Article
Language:English
Published: The Company of Biologists 2017-09-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/10/9/1075