Liquid Chromatography-Tandem Mass Spectrometry Method for Detection and Quantification of Meloxicam and 5′-Carboxymeloxicam in Oral Fluid Samples

Liquid Chromatography-Tandem Mass Spectrometry Method for Detection and Quantification of Meloxicam and 5′-Carboxymeloxicam in Oral Fluid Samples

A sensitive, selective and particularly fast method of liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed and validated for the determination of meloxicam and its main metabolite, 5′-carboxymeloxicam, in oral fluid samples. Meloxicam and its major metabolite were separated using...

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Bibliographic Details
Main Authors: Gabriela Moraes Oliveira, Thiago José Dionísio, Viviane Silva Siqueira-Sandrin, Leticia Alves de Lima Ferrari, Bella Luna Colombini-Ishikiriama, Flávio Augusto Cardoso Faria, Carlos Ferreira Santos, Adriana Maria Calvo
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Metabolites
Subjects:
meloxicam
5′-carboxymeloxicam
mass spectrometry
oral fluid
Online Access:https://www.mdpi.com/2218-1989/13/6/755

Internet

https://www.mdpi.com/2218-1989/13/6/755

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