Dexamethasone down-regulates the expression of microRNA-155 in the livers of septic mice.

To investigate the expression of microRNA-155 (miRNA-155) in the livers of mice with lipopolysaccharide (LPS)-induced sepsis and to determine the role of dexamethasone (DXM) in the regulation of miRNA-155 expression, we pretreated mice with or without DXM prior to LPS exposure. Our study demonstrate...

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Bibliographic Details
Main Authors: Zhong-hua Wang, Yan-bing Liang, Hao Tang, Zhi-bin Chen, Zhen-yu Li, Xu-chu Hu, Zhong-fu Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823654?pdf=render