Autologous Genetically Enriched Leucoconcentrate in the Preventive and Acute Phases of Stroke Treatment in a Mini-Pig Model

Autologous Genetically Enriched Leucoconcentrate in the Preventive and Acute Phases of Stroke Treatment in a Mini-Pig Model

The natural limitations of regeneration in the CNS are major problems for the treatment of neurological disorders, including ischaemic brain strokes. Among the approaches being actively developed to inhibit post-ischaemic negative consequences is the delivery of therapeutic genes encoding neuroprote...

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Bibliographic Details
Main Authors: Zufar Safiullov, Andrei Izmailov, Mikhail Sokolov, Vage Markosyan, Grayr Kundakchan, Ravil Garifulin, Maksim Shmarov, Boris Naroditsky, Denis Logunov, Rustem Islamov
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceutics
Subjects:
autologous genetically enriched leucoconcentrate
chimeric adenoviral vector
vascular endothelial growth factor
glial-cell-line-derived neurotrophic factor
neural cell adhesion molecule
personalized cell-mediated gene therapy
Online Access:https://www.mdpi.com/1999-4923/14/10/2209

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https://www.mdpi.com/1999-4923/14/10/2209

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