Dexamethasone Modulates the Dynamics of Wnt Signaling in Human Trabecular Meshwork Cells

Dexamethasone Modulates the Dynamics of Wnt Signaling in Human Trabecular Meshwork Cells

Trabecular meshwork (TM) tissue is highly specialized, and its structural integrity is crucial for maintaining homeostatic intraocular pressure (IOP). The administration of glucocorticoids, such as dexamethasone (DEX), can perturb the TM structure and significantly increase IOP in susceptible indivi...

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Bibliographic Details
Main Authors: Chi Zhang, Elizabeth Tannous, Alseena Thomas, Natalia Jung, Edmond Ma, Jie J. Zheng
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Vision
Subjects:
trabecular meshwork
Wnt signaling
myocilin
glaucoma
Online Access:https://www.mdpi.com/2411-5150/7/2/43

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https://www.mdpi.com/2411-5150/7/2/43

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