Expression quantitative trait methylation analysis elucidates gene regulatory effects of DNA methylation: the Framingham Heart Study

Expression quantitative trait methylation analysis elucidates gene regulatory effects of DNA methylation: the Framingham Heart Study

Abstract Expression quantitative trait methylation (eQTM) analysis identifies DNA CpG sites at which methylation is associated with gene expression. The present study describes an eQTM resource of CpG-transcript pairs derived from whole blood DNA methylation and RNA sequencing gene expression data i...

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Main Authors: Amena Keshawarz, Helena Bui, Roby Joehanes, Jiantao Ma, Chunyu Liu, Tianxiao Huan, Shih-Jen Hwang, Brandon Tejada, Meera Sooda, Paul Courchesne, Peter J. Munson, Cumhur Y. Demirkale, Chen Yao, Nancy L. Heard-Costa, Achilleas N. Pitsillides, Honghuang Lin, Ching-Ti Liu, Yuxuan Wang, Gina M. Peloso, Jessica Lundin, Jeffrey Haessler, Zhaohui Du, Michael Cho, Craig P. Hersh, Peter Castaldi, Laura M. Raffield, Jia Wen, Yun Li, Alexander P. Reiner, Mike Feolo, Nataliya Sharopova, Ramachandran S. Vasan, Dawn L. DeMeo, April P. Carson, Charles Kooperberg, Daniel Levy
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39936-3

Internet

https://doi.org/10.1038/s41598-023-39936-3

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