Fusobacterium nucleatum infection-induced neurodegeneration and abnormal gut microbiota composition in Alzheimer’s disease-like rats

Fusobacterium nucleatum infection-induced neurodegeneration and abnormal gut microbiota composition in Alzheimer’s disease-like rats

ObjectiveTo explore whether Fusobacterium nucleatum could lead to behavioral and pathological changes in Alzheimer’s disease (AD)-like model rat and whether they could affect the gut microbiota.MethodsThe cognitive ability and alveolar bone loss of Sprague-Dawley (SD) rats were tested by Morris wate...

Full description

Bibliographic Details
Main Authors: Caixia Yan, Qilin Diao, Yuxi Zhao, Cheng Zhang, Xiaoya He, Ruijie Huang, Yan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neuroscience
Subjects:
periodontitis
Alzheimer’s disease
Fusobacterium nucleatum
Aβ
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.884543/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.884543/full

Similar Items