Application of high-density DNA resequencing microarray for detection and characterization of botulinum neurotoxin-producing clostridia.

Clostridium botulinum and related clostridia express extremely potent toxins known as botulinum neurotoxins (BoNTs) that cause severe, potentially lethal intoxications in humans. These BoNT-producing bacteria are categorized in seven major toxinotypes (A through G) and several subtypes. The high div...

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Bibliographic Details
Main Authors: Jessica Vanhomwegen, Nicolas Berthet, Christelle Mazuet, Ghislaine Guigon, Tatiana Vallaeys, Rayna Stamboliyska, Philippe Dubois, Giulia C Kennedy, Stewart T Cole, Valérie Caro, Jean-Claude Manuguerra, Michel-Robert Popoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688605?pdf=render