AlphaFold2 reveals commonalities and novelties in protein structure space for 21 model organisms

A new protein domain classification protocol incorporating deep learning strategies for detecting sequence and structure similarities between domain is used to systematically study and analyse the predicted AlphaFold2 structural models for proteins of 21 organisms.

Bibliographic Details
Main Authors: Nicola Bordin, Ian Sillitoe, Vamsi Nallapareddy, Clemens Rauer, Su Datt Lam, Vaishali P. Waman, Neeladri Sen, Michael Heinzinger, Maria Littmann, Stephanie Kim, Sameer Velankar, Martin Steinegger, Burkhard Rost, Christine Orengo
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04488-9