The Neutrophil to Lymphocyte Ratio Is Associated With the Risk of Subsequent Dementia in the Framingham Heart Study

Objective: Active neutrophils are important contributors to Alzheimer’s disease (AD) pathology through the formation of capillary stalls that compromise cerebral blood flow (CBF) and through aberrant neutrophil signaling that advances disease progression. The neutrophil to lymphocyte ratio (NLR) is...

Full description

Bibliographic Details
Main Authors: Jaime Ramos-Cejudo, Andrew D. Johnson, Alexa Beiser, Sudha Seshadri, Joel Salinas, Jeffrey S. Berger, Nathanael R. Fillmore, Nhan Do, Chunlei Zheng, Zanetta Kovbasyuk, Babak A. Ardekani, Omonigho M. Bubu, Ankit Parekh, Antonio Convit, Rebecca A. Betensky, Thomas M. Wisniewski, Ricardo S. Osorio
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.773984/full