Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids.

The bacteriophage phi29 generates large forces to compact its double-stranded DNA genome into a protein capsid by means of a portal motor complex. Several mechanical models for the generation of these high forces by the motor complex predict coupling of DNA translocation to rotation of the head-tail...

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Bibliographic Details
Main Authors: Thorsten Hugel, Jens Michaelis, Craig L Hetherington, Paul J Jardine, Shelley Grimes, Jessica M Walter, Wayne Falk, Dwight L Anderson, Carlos Bustamante
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0050059