Emerging role of different DNA methyltransferases in the pathogenesis of cancer

Emerging role of different DNA methyltransferases in the pathogenesis of cancer

DNA methylation is one of the most essential epigenetic mechanisms to regulate gene expression. DNA methyltransferases (DNMTs) play a vital role in DNA methylation in the genome. In mammals, DNMTs act with some elements to regulate the dynamic DNA methylation patterns of embryonic and adult cells. C...

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Bibliographic Details
Main Authors: Pengcheng Liu, Fan Yang, Lizhi Zhang, Ying Hu, Bangjie Chen, Jianpeng Wang, Lei Su, Mingyue Wu, Wenjian Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
DNMT
cancer
cellular signaling pathways
epigenetics
anticancer therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.958146/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.958146/full

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