A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
Polycomb (PcG) and Trithorax (TrxG) group regulate several hundred target genes with important roles in development and disease. Here the authors combine experiment and theory to provide evidence that the Polycomb/Trithorax system has the potential for a rich repertoire of regulatory modes beyond si...
Main Authors: | Jeannette Reinig, Frank Ruge, Martin Howard, Leonie Ringrose |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-18507-4 |
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