Involvement of yeast HSP90 isoforms in response to stress and cell death induced by acetic acid.

Acetic acid-induced apoptosis in yeast is accompanied by an impairment of the general protein synthesis machinery, yet paradoxically also by the up-regulation of the two isoforms of the heat shock protein 90 (HSP90) chaperone family, Hsc82p and Hsp82p. Herein, we show that impairment of cap-dependen...

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Bibliographic Details
Main Authors: Alexandra Silva, Belém Sampaio-Marques, Angela Fernandes, Laura Carreto, Fernando Rodrigues, Martin Holcik, Manuel A S Santos, Paula Ludovico
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3744546?pdf=render