The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle.

The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle.

BACKGROUND: Previously, we identified the mitotic arrest deficient protein MAD2B (MAD2L2) as a bona fide interactor of the renal cell carcinoma (RCC)-associated protein PRCC. In addition, we found that fusion of PRCC with the transcription factor TFE3 in t(X;1)(p11;q21)-positive RCCs results in an i...

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Bibliographic Details
Main Authors: Klaas Medendorp, Jan J M van Groningen, Lilian Vreede, Lisette Hetterschijt, Wilhelmina H van den Hurk, Diederik R H de Bruijn, Linda Brugmans, Ad Geurts van Kessel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2737141?pdf=render

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http://europepmc.org/articles/PMC2737141?pdf=render

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