Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis

Cutaneous melanoma can be a most challenging neoplasm of high lethality, in part due to its extreme heterogeneity and characteristic aggressive and invasive nature. Indeed, its moniker ‘the great masquerader’ reflects that not all melanomas are created equal in terms of their originating cellular co...

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Bibliographic Details
Main Authors: Cristina Casalou, Hugo Moreiras, Jay M. Mayatra, Aurelie Fabre, Desmond J. Tobin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.878336/full