Radiation-Induced Hypomethylation Triggers Urokinase Plasminogen Activator Transcription in Meningioma Cells

Our previous studies have shown the role of radiation-induced urokinase plasminogen activator (uPA) expression in the progression of meningioma. In the present study, we investigated whether modulation of DNA methylation profiles could regulate uPA expression. Initially, radiation treatment was foun...

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Bibliographic Details
Main Authors: Kiran Kumar Velpula, Venkateswara Rao Gogineni, Arun Kumar Nalla, Dzung H. Dinh, Jasti S. Rao
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800292