Neuronal Nav1.8 Channels as a Novel Therapeutic Target of Acute Atrial Fibrillation Prevention

Neuronal Nav1.8 Channels as a Novel Therapeutic Target of Acute Atrial Fibrillation Prevention

BackgroundGanglionated plexus have been developed as additional ablation targets to improve the outcome of atrial fibrillation (AF) besides pulmonary vein isolation. Recent studies implicated an intimate relationship between neuronal sodium channel Nav1.8 (encoded by SCN10A) and AF. The underlying m...

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Bibliographic Details
Main Authors: XiaoMeng Chen, LiLei Yu, ShaoBo Shi, Hong Jiang, CongXin Huang, Mayurika Desai, YiGang Li, Hector Barajas‐Martinez, Dan Hu
Format: Article
Language:English
Published: Wiley 2016-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atrial fibrillation
electrophysiology
ganglionated plexus
Nav1.8
SCN10A
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.004050

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.116.004050

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