In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection.

In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection.

Humans who experience a primary dengue virus (DENV) infection develop antibodies that preferentially neutralize the homologous serotype responsible for infection. Affected individuals also generate cross-reactive antibodies against heterologous DENV serotypes, which are non-neutralizing. Dengue cros...

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Bibliographic Details
Main Authors: Ruklanthi de Alwis, Martina Beltramello, William B Messer, Soila Sukupolvi-Petty, Wahala M P B Wahala, Annette Kraus, Nicholas P Olivarez, Quang Pham, James D Brien, Wen-Yang Tsai, Wei-Kung Wang, Scott Halstead, Srisakul Kliks, Michael S Diamond, Ralph Baric, Antonio Lanzavecchia, Federica Sallusto, Aravinda M de Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3119640?pdf=render

Internet

http://europepmc.org/articles/PMC3119640?pdf=render

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