Accumulation of sequence variants in genes of Wnt signaling and focal adhesion pathways in human corneas further explains their involvement in keratoconus

Accumulation of sequence variants in genes of Wnt signaling and focal adhesion pathways in human corneas further explains their involvement in keratoconus

Background Keratoconus (KTCN) is a protrusion and thinning of the cornea, resulting in loss of visual acuity. The etiology of KTCN remains unclear. The purpose of this study was to assess the potential involvement of new genetic variants in KTCN etiology based on both the genomic and transcriptomic...

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Bibliographic Details
Main Authors: Justyna A. Karolak, Tomasz Gambin, Malgorzata Rydzanicz, Piotr Polakowski, Rafal Ploski, Jacek P. Szaflik, Marzena Gajecka
Format: Article
Language:English
Published: PeerJ Inc. 2020-04-01
Series:PeerJ
Subjects:
Candidate keratoconus gene
Overrepresentation analysis
Corneal disease
Keratoconus genetics
WNT signaling
Focal adhesion
Online Access:https://peerj.com/articles/8982.pdf

Internet

https://peerj.com/articles/8982.pdf

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