Role of lipids in spheroidal high density lipoproteins.

We study the structure and dynamics of spherical high density lipoprotein (HDL) particles through coarse-grained multi-microsecond molecular dynamics simulations. We simulate both a lipid droplet without the apolipoprotein A-I (apoA-I) and the full HDL particle including two apoA-I molecules surroun...

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Bibliographic Details
Main Authors: Timo Vuorela, Andrea Catte, Perttu S Niemelä, Anette Hall, Marja T Hyvönen, Siewert-Jan Marrink, Mikko Karttunen, Ilpo Vattulainen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2965744?pdf=render