Duox activation in Drosophila Malpighian tubules stimulates intestinal epithelial renewal through a countercurrent flow

Summary: The gut must perform a dual role of protecting the host against toxins and pathogens while harboring mutualistic microbiota. Previous studies suggested that the NADPH oxidase Duox contributes to intestinal homeostasis in Drosophila by producing reactive oxygen species (ROS) in the gut that...

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Bibliographic Details
Main Authors: Zhonggeng Liu, Hongyu Zhang, Bruno Lemaitre, Xiaoxue Li
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724004376