Mass spectrometry detection of G3m and IGHG3 alleles and follow-up of differential mother and neonate IgG3.

Mass spectrometry detection of G3m and IGHG3 alleles and follow-up of differential mother and neonate IgG3.

Mass spectrometry (MS) analysis for detection of immunoglobulins (IG) of the human IgG3 subclass is described that relies on polymorphic amino acids of the heavy gamma3 chains. IgG3 is the most polymorphic human IgG subclass with thirteen G3m allotypes located on the constant CH2 and CH3 domains of...

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Bibliographic Details
Main Authors: Célia Dechavanne, François Guillonneau, Giovanni Chiappetta, Laïla Sago, Prisca Lévy, Virginie Salnot, Evelyne Guitard, François Ehrenmann, Cédric Broussard, Philippe Chafey, Agnès Le Port, Joëlle Vinh, Patrick Mayeux, Jean-Michel Dugoujon, Marie-Paule Lefranc, Florence Migot-Nabias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3457951?pdf=render

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http://europepmc.org/articles/PMC3457951?pdf=render

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