Identification of Target Proteins Involved in Cochlear Hair Cell Progenitor Cytotoxicity following Gentamicin Exposure

Identification of Target Proteins Involved in Cochlear Hair Cell Progenitor Cytotoxicity following Gentamicin Exposure

Given the non-labile, terminal differentiation of inner-ear sensory cells, preserving their function is critical since sensory cell damage results in irreversible hearing loss. Gentamicin-induced cytotoxicity is one of the major causes of sensory cell damage and consequent sensorineural hearing loss...

Full description

Bibliographic Details
Main Authors: Camron Davies, Rahul Mittal, Crystal Y. Li, Hannah Marwede, Jenna Bergman, Nia Hilton, Jeenu Mittal, Sanjoy K. Bhattacharya, Adrien A. Eshraghi
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Journal of Clinical Medicine
Subjects:
HEI-OC1
organ of Corti
gentamicin ototoxicity
mass spectrometry
high-performance liquid chromatography
confocal microscopy
Online Access:https://www.mdpi.com/2077-0383/11/14/4072

Internet

https://www.mdpi.com/2077-0383/11/14/4072

Similar Items