Current Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and Treatment

Hu-antigen R (HuR) is an RNA-binding posttranscriptional regulator that belongs to the Hu/ELAV family. HuR expression levels are modulated by a variety of proteins, microRNAs, chemical compounds, or the microenvironment, and in turn, HuR affects mRNA stability and translation of various genes implic...

Full description

Bibliographic Details
Main Authors: Ioly Kotta-Loizou, Spyridon N. Vasilopoulos, Robert H.A. Coutts, Stamatios Theocharis
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558616301002