Shikonin reactivates TSGs GADD45B and PPP3CC to block NSCLC cell proliferation and migration through JNK/P38/MAPK signaling pathways

Abstract Background Shikonin, a natural naphthoquinone compound extracted from the Chinese traditional herbal medicine “Lithospermum erythrorhizon”, possesses antitumor activity against various cancer types. Tumor-suppressor genes (TSGs) negatively regulate cell growth, proliferation, and differenti...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Yujia Zhao, Dan Wu, Zhenkai Fu, Wenna Liu, Yu Yao, Ying Liang
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: BMC 2024-01-01
Sraith:BMC Complementary Medicine and Therapies
Rochtain ar líne:https://doi.org/10.1186/s12906-023-04306-z