Prolonged Exposure to Oxaliplatin during HIPEC Improves Effectiveness in a Preclinical Micrometastasis Model

Prolonged Exposure to Oxaliplatin during HIPEC Improves Effectiveness in a Preclinical Micrometastasis Model

Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) was considered a promising treatment for patients with peritoneal metastasis from colorectal cancer. However, the recently published randomized controlled PRODIGE 7 trial failed to demonstrate survival benefits thr...

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Bibliographic Details
Main Authors: Nick Seyfried, Can Yurttas, Markus Burkard, Benedikt Oswald, Alexander Tolios, Franziska Herster, Joseph Kauer, Tarkan Jäger, Ingmar Königsrainer, Karolin Thiel, Markus Quante, Hans-Georg Rammensee, Sascha Venturelli, Matthias Schwab, Alfred Königsrainer, Stefan Beckert, Markus W. Löffler
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
PRODIGE 7 trial
peritoneal metastasis
peritoneal carcinomatosis
colorectal cancer
micrometastasis model
Online Access:https://www.mdpi.com/2072-6694/14/5/1158

Internet

https://www.mdpi.com/2072-6694/14/5/1158

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