The Copper Reduction Potential Determines the Reductive Cytotoxicity: Relevance to the Design of Metal–Organic Antitumor Drugs

The Copper Reduction Potential Determines the Reductive Cytotoxicity: Relevance to the Design of Metal–Organic Antitumor Drugs

Copper–organic compounds have gained momentum as potent antitumor drug candidates largely due to their ability to generate an oxidative burst upon the transition of Cu<sup>2+</sup> to Cu<sup>1+</sup> triggered by the exogenous-reducing agents. We have reported the differentia...

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Bibliographic Details
Main Authors: Elena K. Beloglazkina, Anna A. Moiseeva, Sergey A. Tsymbal, Dmitry A. Guk, Mikhail A. Kuzmin, Olga O. Krasnovskaya, Roman S. Borisov, Elena S. Barskaya, Victor A. Tafeenko, Victoria M. Alpatova, Andrei V. Zaitsev, Alexander V. Finko, Valentina A. Ol’shevskaya, Alexander A. Shtil
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molecules
Subjects:
copper
redox reactions
electrochemistry
tumor cells
cytotoxicity
medicinal chemistry
Online Access:https://www.mdpi.com/1420-3049/29/5/1032

Internet

https://www.mdpi.com/1420-3049/29/5/1032

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