Construction of Streptomyces coelicolor A3(2) mutants that exclusively produce NA4/NA6 intermediates of agarose metabolism through mutation induction

Abstract NA4/NA6, an intermediate degradation product of β-agarase, is a high value-added product with anticancer, anti-obesity, and anti-diabetic effects. Therefore, a method that enables the efficient production of NA4/NA6 would be useful from economic and medical perspectives. In this study, we a...

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Bibliographic Details
Main Authors: Jina Kim, Eun Joo Kim, Hye-Jeong Ko, Yeon-Hee Lee, Soon-Kwang Hong, Miyoung Shin, Je Hyeon Lee, Woori Kwak
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46410-7