Deep sequencing reveals new roles for MuB in transposition immunity and target-capture, and redefines the insular Ter region of E. coli

Abstract Background The target capture protein MuB is responsible for the high efficiency of phage Mu transposition within the E. coli genome. However, some targets are off-limits, such as regions immediately outside the Mu ends (cis-immunity) as well as the entire ~ 37 kb genome of Mu (Mu genome im...

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Bibliographic Details
Main Authors: David M. Walker, Rasika M. Harshey
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Mobile DNA
Online Access:http://link.springer.com/article/10.1186/s13100-020-00217-9