A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protect Pigs against a Virulent CSFV Challenge

A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protect Pigs against a Virulent CSFV Challenge

Classical swine fever (CSF) remains one of the most economically significant viral diseases affecting domestic pigs and wild boars worldwide. To develop a safe and effective vaccine against CSF, we have constructed a triple gene-deleted pseudorabies virus (PRVtmv)-vectored bivalent subunit vaccine a...

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Bibliographic Details
Main Authors: Ediane Silva, Elizabeth Medina-Ramirez, Selvaraj Pavulraj, Douglas P. Gladue, Manuel Borca, Shafiqul I. Chowdhury
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Viruses
Subjects:
pseudorabies virus
triple mutant
vectored vaccine
PCV2 capsid
classical swine fever virus (CSFV)
glycoproteins E2 and E<sup>rns</sup>
Online Access:https://www.mdpi.com/1999-4915/15/11/2143

Internet

https://www.mdpi.com/1999-4915/15/11/2143

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